89-7747-82 Recombinant Human Frizzled-6/FZD6 Protein (Fc Tag) 100ug PKSH030518
[Elabscience]
特徴
- 背景：This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_003497.2
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Val153
- 遺伝子構造：A DNA sequence encoding the human FZD6 (NP_003497.2) (Met1-Val153) was expressed with the Fc region of mouse IgG1 at the C-terminus.
- 別名（遺伝子名）：FZ-6;FZ6;HFZ6;NDNC10
- 分子量：42 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105389-Elabscience-PKSH030518.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7747-81
Recombinant Human Frizzled-6/FZD6 Protein (Fc Tag) 20ug
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89-7747-82
Recombinant Human Frizzled-6/FZD6 Protein (Fc Tag) 100ug
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