89-7746-85 ［取扱停止］Recombinant Human NFASC/Neurofascin protein (Fc Tag) 200ug PKSH030462
[Elabscience]
特徴
- 背景：NFASC, also known as neurofascin, belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM family. It contains 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. NFASC functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. NFASC links the AIS extracellular matrix to the intracellular cytoskeleton.
仕様
- サイズ：200ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_001005388.2
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Gln939
- 遺伝子構造：A DNA sequence encoding the human NFASC (XP_011507630.1) (Met1-Gln939) was expressed with the Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：NF;NRCAML
- 分子量：130 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37248-Elabscience-PKSH030462.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7746-84
Recombinant Human NFASC/Neurofascin protein (Fc Tag) 50ug
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89-7746-85
Recombinant Human NFASC/Neurofascin protein (Fc Tag) 200ug
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