89-7746-83 ［取扱停止］Recombinant Human LAG3/CD223 Protein (Fc Tag) 200ug PKSH030460
[Elabscience]
特徴
- 背景：LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells. It also acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo.Immune CheckpointImmune Checkpoint Targets Co-inhibitory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
仕様
- サイズ：200ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> (3.0+91.0+3.1) % as determined by reducing SDS-PAGE..
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_002277.4
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Leu450
- 遺伝子構造：A DNA sequence encoding the human LAG3 (NP_002277.4) (Met1-Leu450) was expressed with the Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：Lymphocyte activation gene 3 protein;LAG3;LAG-3;Protein FDC;CD223;LAG-3
- 分子量：72.3 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37246-Elabscience-PKSH030460.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7746-83
Recombinant Human LAG3/CD223 Protein (Fc Tag) 200ug
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89-7746-82
Recombinant Human LAG3/CD223 Protein (Fc Tag) 50ug
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