89-7745-77 ［取扱停止］Recombinant Human CSNK1A1/CKI-alpha/CK1 Protein (GST Tag)(Active) 20ug PKSH030400
[Elabscience]
特徴
- 背景：Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. High expression of CSNK2A1, or concomitantly high expression of CSNK2A1, are independent prognostic factors of poor survival in NSCLC patients. CSNK2A1 are useful prognosis markers in non-small cell lung cancer (NSCLC) patients after complete resection, independent of lymph node metastasis status. CSNK1A1 can phosphorylate a large number of proteins. It participates in Wnt signaling. It phosphorylates CTNNB1 at 'Ser-45'. CSNK1A1 may play a role in segregating chromosomes during mitosis.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P48729-1
- タグ種類：N-GST
- アミノ酸配列：Met 1-Phe 337
- 遺伝子構造：A DNA sequence encoding the full length of human CSNK1A1 isoform 1 (P48729-1) (Met 1-Phe 337) was expressed with the GST tag at the N-terminus.
- 活性：The specific activity was determined to be 30 nmol/min/mg using casein as substrate.
- 別名（遺伝子名）：CK1;CK1a;CKIa;HEL-S-77p;HLCDGP1;PRO2975
- 分子量：65.2 kDa
- 組成：Supplied as sterile 20mM Tris, 500mM NaCl, 2mM GSH, pH 7.4
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37209-Elabscience-PKSH030400.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7745-77
Recombinant Human CSNK1A1/CKI-alpha/CK1 Protein (GST Tag)(Active) 20ug
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89-7745-78
Recombinant Human CSNK1A1/CKI-alpha/CK1 Protein (GST Tag)(Active) 50ug
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