背景：Hexokinase-3, also known as Hexokinase type III, HKIII and HK3, is a protein which belongs to the hexokinase family. Hexokinase-3 / HK3 is an enzyme which in humans is encoded by the HK2 gene. Hexokinases phosphorylate glucose to produce glucose 6-phosphate, committing glucose to the glycolytic pathway. In mammalian tissues hexokinase exists as four isoenzymes encoded by distinct genes. These proteins are homologous and are organized in two homologous domains, with the exception of hexokinase type IV which has only one. This organization is believed to be the result of a duplication and tandem fusion event involving the gene encoding for the ancestral hexokinase. The gene encodes hexokinase-3. Similar to hexokinases-1 and hexokinases-2, this allosteric enzyme is inhibited by its product glucose 6-phosphate.
仕様
サイズ：50ug
種由来：Human
発現宿主：Baculovirus-Insect Cells
純度：> 85 % as determined by reducing SDS-PAGE.
エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
アクセッションＮｏ．：P52790
タグ種類：N-His & GST
アミノ酸配列：Met 1-Val 923
遺伝子構造：A DNA sequence encoding the human HK3 (P52790) (Met 1-Val 923) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
別名（遺伝子名）：HKIII;HXK3
分子量：127 kDa
組成：Supplied as sterile 50mM Tris, 100mM NaCl, pH 7.4
保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
