89-7744-74 ［取扱停止］Recombinant Human MARK3/CTAK1/EMK-2 Protein (His & GST Tag)(Active) 50ug PKSH030341
[Elabscience]
特徴
- 背景：MAP / microtubule affinity-regulating kinase 3, also known as C-TAK1, cTAK1, Cdc25C-associated protein kinase 1, ELKL motif kinase 2, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Serine/threonine-protein kinase p78, MARK3, CTAK1 and EMK2, is a ubiquitous expressed protein which belongs to the protein kinase superfamily, CAMK Ser / Thr protein kinase family and MARK subfamily. MARK3 contains one KA1 (kinase-associated) domain, one protein kinase domain and one UBA domain. The Par-1 / MARK protein kinases play a pivotal role in establishing cellular polarity. This family of kinases contains a unique domain architecture, in which a ubiquitin-associated (UBA) domain is located C-terminal to the kinase domain. MARKs / PAR-1 are common regulators of cell polarity that are conserved from nematode to human. All of these kinases have a highly conserved C-terminal domain, which is termed the kinase-associated domain 1 (KA1).
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 88 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：AAH24773.1
- タグ種類：N-His & GST
- アミノ酸配列：Met 1-Leu 729
- 遺伝子構造：A DNA sequence encoding full length of human MARK3 (AAH24773.1) (Met 1-Leu 729) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 活性：The specific activity was determined to be 7 nmol/min/mg using synthetic CHKtide peptide (KKKVSRSGLYRSPSMPENLNRPR) as substrate.
- 別名（遺伝子名）：CTAK1;KP78;Par-1a;PAR1A
- 分子量：109.3 kDa
- 組成：Supplied as sterile 20mM Tris, 500mM NaCl, 0.25mM DTT, 0.1mM PMSF, 0.1mM EDTA, pH 7.4, 10% gly
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37166-Elabscience-PKSH030341.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7744-74
Recombinant Human MARK3/CTAK1/EMK-2 Protein (His & GST Tag)(Active) 50ug
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89-7744-73
Recombinant Human MARK3/CTAK1/EMK-2 Protein (His & GST Tag)(Active) 20ug
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