89-7744-45 Recombinant Human ROR1 Protein (aa 453-783, His & GST Tag)(Active) 50ug PKSH030321
[Elabscience]
特徴
- 背景：Receptor tyrosine kinase-like orphan receptor 1 (ROR1), also known as neurotrophic tyrosine kinase, it is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Human ROR1 is a type I transmembrane protein with 937 amino acids (aa) in length. It contains a 29 aa signal sequence, a 377 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 510 aa cytoplasmic region. ROR1 expressed strongly in human heart, lung and kidney, but weakly in the CNS. At developmental stage, it expressed at high levels during early embryonic development. ROR1 has been shown to have very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. It may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：AAA60275.1
- タグ種類：N-His & GST
- アミノ酸配列：Met 453-Asn783
- 遺伝子構造：A DNA sequence encoding the human ROR1 (AAA60275.1) (Met453-Asn783) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 活性：The specific activity was determined to be 0.3 nmol/min/mg using MBP as substrate.
- 別名（遺伝子名）：dJ537F10.1;NTRKR1
- 分子量：65.3 kDa
- 組成：Supplied as sterile 20mM Tris, 500mM NaCl, 2mM GSH, 3mM DTT, 10% glycerol, pH 7.4
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105339-Elabscience-PKSH030321.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7744-45
Recombinant Human ROR1 Protein (aa 453-783, His & GST Tag)(Active) 50ug
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89-7744-44
Recombinant Human ROR1 Protein (aa 453-783, His & GST Tag)(Active) 20ug
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