背景:CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis.
仕様
サイズ:50ug
種由来:Human
発現宿主:Baculovirus-Insect Cells
純度:> 95 % as determined by reducing SDS-PAGE.
エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
アクセッションNo.:P30085
タグ種類:N-His
アミノ酸配列:Met 1-Gly 196
遺伝子構造:A DNA sequence encoding the human CMPK1 (P30085) (Met1-Gly196) was fused with a polyhistide tag at the N-terminus.