89-7744-35 Recombinant Human SPHK1/Sphingosine Kinase 1 Protein (Active) 50ug PKSH030315
[Elabscience]
特徴
- 背景：SPHK1; also known as sphingosine Kinase 1; catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation; survival; migration; cytoskeletal organization; and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory; antiapoptotic; and immune processes.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q9NYA1-1
- アミノ酸配列：Met 1-Leu 384
- 遺伝子構造：A DNA sequence encoding the human SPHK1 (Q9NYA1-1)(Met1-Leu384) was fused with two additional amino acids (Gly & Pro) at the N-terminus.
- 活性：The specific activity was determined to be 1028 nmol/min/mg using Sphingosine Kinase Substrate as substrate.
- 別名（遺伝子名）：SPHK;SPHK1;SPK
- 分子量：42.7 kDa
- 組成：Supplied as sterile 20mM Tris; 500mM NaCl; 10% glycerol; pH 8.0
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37148-Elabscience-PKSH030315.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7744-34
Recombinant Human SPHK1/Sphingosine Kinase 1 Protein (Active) 20ug
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89-7744-35
Recombinant Human SPHK1/Sphingosine Kinase 1 Protein (Active) 50ug
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