89-7608-76　［取扱停止］PPARA Polyclonal Antibody 200uL　E-AB-40069

特徴

• 主な研究分野例：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
• 背景：Peroxisome proliferator-activated receptor alpha (PPARA) is a ligand-activated transcription factor that belongs to the PPAR nuclear receptor superfamily. PPARA is essential in the modulation of lipid transport and metabolism, mainly through activating mitochondrial and peroxisomal fatty acid β-oxidation pathways. In addition, PPARA seems to decrease inflammation mainly through direct interaction with NF-κB, causing inhibition of its signaling pathway or reducing the activated levels of NF-κB and subsequent inflammation. Furthermore, PPARA was implicated in the attenuation of oxidative stress in alcoholic liver disease when treated with polyenephosphatidylcholine through downregulation of ROS-generating enzymes such as ethanol-inducible cytochrome P450 2E1 (CYP2E1), acyl-CoA oxidase, and NADPH oxidase.

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：WB
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：2 mg/mL
• 抗原：Recombinant human Peroxisome proliferator-activated receptor alpha protein
• 緩衝液：PBS with 0.05％ Proclin300 and 50％ glycerol, pH7.4.
• 精製方法：Affinity purification
• 希釈倍率：WB 1：500-1：1000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-26250-Elabscience-E-AB-40069.pdf
• サイズ：200uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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