89-7607-72　［取扱停止］Langerin Polyclonal Antibody 20uL　E-AB-40044

特徴

• 主な研究分野例：Metabolism, Signaling transduction
• 背景：Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：IHC
• 交差性：Human,Mouse
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：2 mg/mL
• 抗原：Recombinant human C-type lectin domain family 4 member K protein
• 緩衝液：PBS with 0.02％ sodium azide and 50％ glycerol pH 7.4.
• 精製方法：Affinity purification
• 希釈倍率：IHC 1：50-1：100
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-26225-Elabscience-E-AB-40044.pdf
• サイズ：20uL
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