89-7605-52　［取扱停止］MYBPC3 Polyclonal Antibody 120uL　E-AB-36520

特徴

• 主な研究分野例：Cardiovascular
• 背景：MYBPC3 (Myosin Binding Protein C, Cardiac) is a Protein Coding gene. Diseases associated with MYBPC3 include Cardiomyopathy, Hypertrophic, 4 and Left Ventricular Noncompaction 10. Among its related pathways are Cardiac conduction and Dilated cardiomyopathy. GO annotations related to this gene include identical protein binding and structural constituent of muscle. An important paralog of this gene is MYBPC2.MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：WB,ELISA
• 交差性：Human,Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1mg/mL
• 抗原：Synthesized peptide derived from human MYBPC3 Polyclonal
• 緩衝液：PBS with 0.02％ sodium azide,0.5％ BSA and 50％ glycerol pH 7.4.
• 精製方法：Affinity purification
• 希釈倍率：WB 1：500-2000, ELISA 1：10000-20000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-42530-Elabscience-E-AB-36520.pdf
• サイズ：120uL
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