特徴
- 主な研究分野例:Cancer, Cardiovascular, Immunology, Signal Transduction
- 背景:This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.CMA1 (Chymase 1) is a Protein Coding gene. Diseases associated with CMA1 include Urticaria Pigmentosa and Urticaria. Among its related pathways are Degradation of the extracellular matrix and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. GO annotations related to this gene include serine-type endopeptidase activity and peptide binding. An important paralog of this gene is GZMB.
仕様
- 抗体タイプ:ポリクローナル 抗体
- アプリケーション:WB,ELISA
- 交差性:Human
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1mg/mL
- 抗原:Synthesized peptide derived from the Internal region of human Chymase.
- 緩衝液:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
- 精製方法:Affinity purification
- 希釈倍率:WB 1:500-1:2000, ELISA 1:20000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-29718-Elabscience-E-AB-33393.pdf
- サイズ:120uL
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7602-36
Chymase Polyclonal Antibody 60uL
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89-7602-35
Chymase Polyclonal Antibody 20uL
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89-7602-37
Chymase Polyclonal Antibody 120uL
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89-7602-38
Chymase Polyclonal Antibody 200uL
|
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