89-7602-18　［取扱停止］Myosin VI Polyclonal Antibody 200uL　E-AB-33342

特徴

• 主な研究分野例：Cancer, Signal Transduction
• 背景：This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. MYO6 (Myosin VI) is a Protein Coding gene. Diseases associated with MYO6 include Deafness, Autosomal Dominant 22 and Deafness, Autosomal Recessive 37. Among its related pathways are PAK Pathway and Vesicle-mediated transport. GO annotations related to this gene include actin binding and actin filament binding. An important paralog of this gene is MYO7A.

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：WB,IHC-p,ELISA
• 交差性：Human,Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1mg/mL
• 抗原：Synthesized peptide derived from the N-terminal region of human Myosin VI
• 緩衝液：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
• 精製方法：Affinity purification
• 希釈倍率：WB 1：500-1：2000, IHC 1：100-300, ELISA 1：5000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-29667-Elabscience-E-AB-33342.pdf
• サイズ：200uL
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