特徴
- 主な研究分野例:Epigenetics and Nuclear Signaling, Signal Transduction
- 背景:This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.ZFP36L1 (ZFP36 Ring Finger Protein Like 1) is a Protein Coding gene. Diseases associated with ZFP36L1 include Sotos Syndrome 1. Among its related pathways are Validated targets of C-MYC transcriptional repression and PI3K / Akt Signaling. GO annotations related to this gene include poly(A) RNA binding and mRNA binding. An important paralog of this gene is ZFP36L2.
仕様
- 抗体タイプ:ポリクローナル 抗体
- アプリケーション:WB,IHC-p,ELISA
- 交差性:Human,Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1mg/mL
- 抗原:Synthesized peptide derived from human TIS11B around the non-phosphorylation site of S92.
- 緩衝液:PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
- 精製方法:Affinity purification
- 希釈倍率:WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-29435-Elabscience-E-AB-33110.pdf
- サイズ:200uL
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- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7601-32
TIS11B Polyclonal Antibody 120uL
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89-7601-33
TIS11B Polyclonal Antibody 200uL
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89-7601-30
TIS11B Polyclonal Antibody 20uL
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89-7601-31
TIS11B Polyclonal Antibody 60uL
|
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