特徴
- 主な研究分野例:Cancer, Epigenetics and Nuclear Signaling
- 背景:This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.NPM1 (Nucleophosmin) is a Protein Coding gene. Diseases associated with NPM1 include Leukemia, Acute Myeloid and Lymphomatoid Papulosis. Among its related pathways are Validated targets of C-MYC transcriptional activation and Chromosome Maintenance. GO annotations related to this gene include nucleic acid binding and protein homodimerization activity. An important paralog of this gene is NPM2.
仕様
- 抗体タイプ:ポリクローナル 抗体
- アプリケーション:WB,IHC-p,ELISA
- 交差性:Human,Mouse,Rat,Monkey
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1mg/mL
- 抗原:Synthesized peptide derived from the N-terminal region of human Nucleophosmin
- 緩衝液:PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
- 精製方法:Affinity purification
- 希釈倍率:WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-28615-Elabscience-E-AB-32290.pdf
- サイズ:20uL
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- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7597-92
Nucleophosmin Polyclonal Antibody 120uL
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89-7597-90
Nucleophosmin Polyclonal Antibody 20uL
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89-7597-93
Nucleophosmin Polyclonal Antibody 200uL
|
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89-7597-91
Nucleophosmin Polyclonal Antibody 60uL
|
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