特徴
- 主な研究分野例:Cancer, Cell Biology, Metabolism, Signal Transduction
- 背景:Bcl x is a member of the Bcl 2 family of proteins, which function as regulators of apoptosis. It may provide neuroprotection against ischemic brian injury. Bcl x has two isoforms, Bcl xl (long) a 241 amino acid protein and Bcl xs (short) a 178 amino acid protein lacking a 63 amino acid domain that is well conserved among members of the Bcl2 family. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.
仕様
- 抗体タイプ:ポリクローナル 抗体
- アプリケーション:WB,IHC-p,IF,ELISA
- 交差性:Human,Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1 mg/mL
- 抗原:Synthesized peptide derived from human Bcl-x around the non-phosphorylation site of Thr47.
- 緩衝液:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
- 精製方法:Affinity purification
- 希釈倍率:WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-26965-Elabscience-E-AB-30640.pdf
- サイズ:200uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7590-16
Bcl-x Polyclonal Antibody 60uL
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89-7590-15
Bcl-x Polyclonal Antibody 20uL
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89-7590-18
Bcl-x Polyclonal Antibody 200uL
|
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89-7590-17
Bcl-x Polyclonal Antibody 120uL
|
よくあるご質問(FAQ)
掲載カタログ情報
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