89-7589-63　AMPKa1/2 Polyclonal Antibody 60uL　E-AB-30491

特徴

• 主な研究分野例：Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction
• 背景：AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic a subunit and regulatory b and γ subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively.

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：WB,IHC-p,ELISA
• 交差性：Human,Mouse,Rat,Monkey
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1 mg/mL
• 抗原：Synthesized peptide derived from human AMPKa1/2 around the non-phosphorylation site of Thr183/172.
• 緩衝液：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
• 精製方法：Affinity purification
• 希釈倍率：WB 1：500-1：2000, IHC 1：100-1：300, ELISA 1：40000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-26816-Elabscience-E-AB-30491.pdf
• サイズ：60uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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