特徴
- 主な研究分野例:Cancer, Epigenetics and Nuclear Signaling
- 背景:This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.
仕様
- 抗体タイプ:ポリクローナル 抗体
- アプリケーション:WB,ELISA
- 交差性:Human
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1mg/mL
- 抗原:Synthesized peptide derived from human EKLF around the non-acetylation site of K274.
- 緩衝液:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
- 精製方法:Affinity purification
- 希釈倍率:WB 1:500-1:2000, ELISA 1:20000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-26497-Elabscience-E-AB-30172.pdf
- サイズ:120uL
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- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7588-37
EKLF Polyclonal Antibody 20uL
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89-7588-40
EKLF Polyclonal Antibody 200uL
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89-7588-39
EKLF Polyclonal Antibody 120uL
|
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89-7588-38
EKLF Polyclonal Antibody 60uL
|
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