89-7587-65　Cleaved-Caspase-4 p20 (Q81) Polyclonal Antibody 60uL　E-AB-30021

特徴

• 主な研究分野例：Cancer, Cell Biology, Metabolism
• 背景：This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：WB,IHC-p,ELISA
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1mg/mL
• 抗原：Synthesized peptide derived from the Internal region of human Caspase-4 p20
• 緩衝液：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
• 精製方法：Affinity purification
• 希釈倍率：WB 1：500-1：2000, IHC 1：100-1：300, ELISA 1：40000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-26346-Elabscience-E-AB-30021.pdf
• サイズ：60uL
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