特徴
- 主な研究分野例:Cancer, Cell Biology, Cardiovascular, Metabolism
- 背景:Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro.PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.
仕様
- 抗体タイプ:モノクローナル 抗体
- アプリケーション:IHC-p
- 交差性:Human,Mouse,Rat
- 宿主:Mouse
- アイソタイプ:IgG
- 濃度:1 mg/mL
- 抗原:Synthetic Peptide of MMP2
- 緩衝液:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
- 精製方法:Protein A purification
- 希釈倍率:IHC 1:100-200
- 標識:Unconjugated
- クローナリティ:Monoclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-42091-Elabscience-E-AB-22242.pdf
- サイズ:20uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7586-38
MMP2 Monoclonal Antibody 200uL
|
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89-7586-37
MMP2 Monoclonal Antibody 120uL
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89-7586-35
MMP2 Monoclonal Antibody 20uL
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89-7586-36
MMP2 Monoclonal Antibody 60uL
|
よくあるご質問(FAQ)
掲載カタログ情報
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