89-7582-45　Beclin-1 Monoclonal Antibody 120uL　E-AB-22139

特徴

• 主な研究分野例：Cancer, Epigenetics and Nuclear Signaling, Metabolism, Microbiology, Signal Transduction
• 背景：Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.

仕様

• 抗体タイプ：モノクローナル 抗体
• アプリケーション：WB,IHC-p
• 交差性：Human,Mouse,Rat
• 宿主：Mouse
• アイソタイプ：IgG
• 濃度：1 mg/mL
• 抗原：Synthetic Peptide of Beclin-1
• 緩衝液：PBS with 0.02％ sodium azide, 0.5％ BSA and 50％ glycerol, pH7.4
• 精製方法：Protein A purification
• 希釈倍率：WB 1：1000-2000, IHC 1：100-200
• 標識：Unconjugated
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-41283-Elabscience-E-AB-22139.pdf
• サイズ：120uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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