89-7579-52　IDE Monoclonal Antibody 20uL　E-AB-22041

特徴

• 主な研究分野例：Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience, Signal Transduction
• 背景：This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.

仕様

• 抗体タイプ：モノクローナル 抗体
• アプリケーション：WB,IHC-p,IF
• 交差性：Human
• 宿主：Mouse
• アイソタイプ：IgG
• 濃度：1 mg/mL
• 抗原：Synthetic Peptide
• 緩衝液：PBS with 0.02％ sodium azide and 50％ glycerol pH 7.4.
• 精製方法：Protein A purification
• 希釈倍率：WB 1：500-1：2000, IHC 1：50-300, IF 1：100-1：300
• 標識：Unconjugated
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-24693-Elabscience-E-AB-22041.pdf
• サイズ：20uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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