89-7578-91　Kif 7 Monoclonal Antibody 20uL　E-AB-22026

特徴

• 主な研究分野例：Signal Transduction, Stem Cells
• 背景：This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.

仕様

• 抗体タイプ：モノクローナル 抗体
• アプリケーション：IHC-p,IF
• 交差性：Human,Mouse,Rat
• 宿主：Mouse
• アイソタイプ：IgG
• 濃度：1 mg/mL
• 抗原：Synthetic Peptide
• 緩衝液：PBS with 0.02％ sodium azide and 50％ glycerol pH 7.4.
• 精製方法：Protein A purification
• 希釈倍率：IHC 1：100-1：300, IF 1：50-200
• 標識：Unconjugated
• クローナリティ：Monoclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-24678-Elabscience-E-AB-22026.pdf
• サイズ：20uL
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