89-7577-77 [取扱停止]Phospho-Tuberin (Thr1462) Polyclonal Antibody 200uL E-AB-21941
[Elabscience]特徴
- 主な研究分野例:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
- 背景:In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. Stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro. Mutations in TSC2 lead to constitutive activation of RAP1A in tumors.
仕様
- 抗体タイプ:抗リン酸化 抗体
- アプリケーション:WB,IHC-p,IF,ELISA
- 交差性:Human,Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1 mg/mL
- 抗原:Synthesized peptide derived from human Tuberin around the phosphorylation site of T1462.
- 緩衝液:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
- 精製方法:Affinity purification
- 希釈倍率:IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-41832-Elabscience-E-AB-21941.pdf
- サイズ:200uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7577-74
Phospho-Tuberin (Thr1462) Polyclonal Antibody 20uL
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89-7577-75
Phospho-Tuberin (Thr1462) Polyclonal Antibody 60uL
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89-7577-77
Phospho-Tuberin (Thr1462) Polyclonal Antibody 200uL
|
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89-7577-76
Phospho-Tuberin (Thr1462) Polyclonal Antibody 120uL
|
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