89-7576-65 [取扱停止]Phospho-Amyloid-b (Thr743) Polyclonal Antibody 20uL E-AB-21260
[Elabscience]特徴
- 主な研究分野例:Cancer, Neuroscience
- 背景:Ab derives from APP via proteolytic cleavage by proteases called a-, b- and γ-secretase. The a-secretase cleavage precludes the formation of Ab, while the b- and γ-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain, kidney, heart and spleen, but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1). This antibody can recogniaze the N-terminus of human APP: Soluble APP-alpha and Soluble APP-beta.
仕様
- 抗体タイプ:抗リン酸化 抗体
- アプリケーション:WB,IHC-p,IF,ELISA
- 交差性:Human,Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:1 mg/mL
- 抗原:Synthesized peptide derived from human Amyloid-b around the phosphorylation site of Thr743
- 緩衝液:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
- 精製方法:Affinity purification
- 希釈倍率:WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-25849-Elabscience-E-AB-21260.pdf
- サイズ:20uL
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7576-66
Phospho-Amyloid-b (Thr743) Polyclonal Antibody 60uL
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89-7576-68
Phospho-Amyloid-b (Thr743) Polyclonal Antibody 200uL
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89-7576-67
Phospho-Amyloid-b (Thr743) Polyclonal Antibody 120uL
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89-7576-65
Phospho-Amyloid-b (Thr743) Polyclonal Antibody 20uL
|
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