89-7512-91　［取扱停止］VWA5A Polyclonal Antibody 120uL　E-AB-14788

特徴

• 背景：VWA5A (von Willebrand factor A domain containing 5A), also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein), is a 786 amino acid protein containing one VIT domain and one VWFA domain. VWA5A is expressed at low levels in various tissues, with no expression found in 80% of tumor cell lines. Likely acting as a tumor suppressor gene, deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors, and may have an important role as a potential gene therapy target. Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with an increase in expression of E-cadherin, alpha-catenin, and p53, resulting in a decrease of malignant activity in cells with ectopic expression of VWA5A.

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：WB,IHC,ELISA
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：0.5 mg/mL
• 抗原：Recombinant protein of human VWA5A
• 緩衝液：PBS with 0.05％ sodium azide and 50％ glycerol, PH7.4
• 精製方法：Affinity purification
• 希釈倍率：WB 1：500-1：2000, IHC 1：100-1：300
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-34216-Elabscience-E-AB-14788.pdf
• サイズ：120uL
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