特徴
- 背景:Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.
仕様
- 抗体タイプ:ポリクローナル 抗体
- アプリケーション:WB,IHC,ELISA
- 交差性:Human,Mouse
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:0.5 mg/mL
- 抗原:Recombinant protein of human COX11
- 緩衝液:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
- 精製方法:Affinity purification
- 希釈倍率:WB 1:1000-1:5000, IHC 1:25-1:100
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-33448-Elabscience-E-AB-14015.pdf
- サイズ:20uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7496-86
COX11 Polyclonal Antibody 60uL
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89-7496-88
COX11 Polyclonal Antibody 200uL
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89-7496-85
COX11 Polyclonal Antibody 20uL
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89-7496-87
COX11 Polyclonal Antibody 120uL
|
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掲載カタログ情報
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