89-7495-41　BIN1 Polyclonal Antibody 60uL　E-AB-13951

特徴

• 主な研究分野例：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Microbiology
• 背景：This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：IHC,ELISA
• 交差性：Human
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：0.1 mg/mL
• 抗原：Recombinant protein of human BIN1
• 緩衝液：PBS with 0.05％ sodium azide and 50％ glycerol, PH7.4
• 精製方法：Affinity purification
• 希釈倍率：IHC 1：50-1：200
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-33386-Elabscience-E-AB-13951.pdf
• サイズ：60uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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