特徴
- 主な研究分野例:Cancer, Signal Transduction
- 背景:CrkRS (Cdc2-related kinase, arginine/serine-rich, also designated CRK7 and CRKR) is an ubiquitous protein that appears to localize to the nucleus and link transcription and splicing machinery. CrkRS belongs to the serine/threonine protein kinase family and Cdc2/Cdkx subfamily. CrkRS has extensive proline-rich regions that resemble SH3 and WW domain binding sites, and an RS domain that is characteristic of splicing factors. The protein kinase domain of CrkRS is 89% identical to the CHED protein kinase, also designated CDC2L5 and cell division cycle 2-like 5 (cholinesterase-related cell division controller), however outside the kinase domains the two proteins are unique. Cell cycle control kinases can phosphorylate proteins important for differentiation and apoptosis and provide connections between proliferation, differentiation, apoptosis, and neurocytoskeleton dynamics.
仕様
- 抗体タイプ:ポリクローナル 抗体
- アプリケーション:IHC,ELISA
- 交差性:Human,Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:0.5 mg/mL
- 抗原:Synthetic peptide of human CDK12
- 緩衝液:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
- 精製方法:Affinity purification
- 希釈倍率:IHC 1:25-1:100
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-32612-Elabscience-E-AB-13172.pdf
- サイズ:20uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7480-50
CDK12 Polyclonal Antibody 60uL
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89-7480-49
CDK12 Polyclonal Antibody 20uL
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89-7480-52
CDK12 Polyclonal Antibody 200uL
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89-7480-51
CDK12 Polyclonal Antibody 120uL
|
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