89-7478-71　CBL Polyclonal Antibody 20uL　E-AB-13099

特徴

• 主な研究分野例：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction
• 背景：This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：WB,ELISA
• 交差性：Human,Mouse
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：0.4 mg/mL
• 抗原：Synthetic peptide of human CBL
• 緩衝液：PBS with 0.05％ sodium azide and 50％ glycerol, PH7.4
• 精製方法：Affinity purification
• 希釈倍率：WB 1：500-1：2000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-32539-Elabscience-E-AB-13099.pdf
• サイズ：20uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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