特徴
- 主な研究分野例:Signal Transduction
- 背景:This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.
仕様
- 抗体タイプ:ポリクローナル 抗体
- アプリケーション:IHC,ELISA
- 交差性:Human
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:0.6 mg/mL
- 抗原:Synthetic peptide of human CLDN8
- 緩衝液:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
- 精製方法:Affinity purification
- 希釈倍率:IHC 1:50-1:200
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-31908-Elabscience-E-AB-12457.pdf
- サイズ:60uL
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7464-41
CLDN8 Polyclonal Antibody 20uL
|
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89-7464-44
CLDN8 Polyclonal Antibody 200uL
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89-7464-42
CLDN8 Polyclonal Antibody 60uL
|
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89-7464-43
CLDN8 Polyclonal Antibody 120uL
|
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