89-7464-05　GRPR Polyclonal Antibody 20uL　E-AB-12444

特徴

• 主な研究分野例：Cancer, Neuroscience, Signal Transduction
• 背景：Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：WB,IHC,ELISA
• 交差性：Human,Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：1.1 mg/mL
• 抗原：Synthetic peptide of human GRPR
• 緩衝液：PBS with 0.05％ sodium azide and 50％ glycerol, PH7.4
• 精製方法：Affinity purification
• 希釈倍率：WB 1：200-1：1000, IHC 1：50-1：200
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-31895-Elabscience-E-AB-12444.pdf
• サイズ：20uL
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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