特徴
- 主な研究分野例:Cancer, Signal Transduction
- 背景:DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.
仕様
- 抗体タイプ:ポリクローナル 抗体
- アプリケーション:WB,IHC,ELISA
- 交差性:Human,Mouse,Rat
- 宿主:Rabbit
- アイソタイプ:IgG
- 濃度:0.5 mg/mL
- 抗原:Recombinant protein of human DNAJA1
- 緩衝液:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
- 精製方法:Affinity purification
- 希釈倍率:WB 1:500-1:2000, IHC 1:100-1:300
- 標識:Unconjugated
- クローナリティ:Polyclonal
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-31353-Elabscience-E-AB-11313.pdf
- サイズ:200uL
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7452-75
DNAJA1 Polyclonal Antibody 120uL
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89-7452-76
DNAJA1 Polyclonal Antibody 200uL
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89-7452-73
DNAJA1 Polyclonal Antibody 20uL
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89-7452-74
DNAJA1 Polyclonal Antibody 60uL
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