89-7433-35　［取扱停止］PIWIL4 Polyclonal Antibody 20uL　E-AB-10542

特徴

• 主な研究分野例：Cancer, Epigenetics and Nuclear Signaling
• 背景：PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association.

仕様

• 抗体タイプ：ポリクローナル 抗体
• アプリケーション：WB,ELISA
• 交差性：Human,Mouse,Rat
• 宿主：Rabbit
• アイソタイプ：IgG
• 濃度：0.4 mg/mL
• 抗原：Recombinant protein of human PIWIL4
• 緩衝液：PBS with 0.05％ sodium azide and 50％ glycerol, PH7.4
• 精製方法：Affinity purification
• 希釈倍率：WB 1：500-1：2000
• 標識：Unconjugated
• クローナリティ：Polyclonal
• メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-30587-Elabscience-E-AB-10542.pdf
• サイズ：20uL
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