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89-6315-19 Smad4 Polyclonal Antibody 60μL, E-AB-34159 E-AB-34159

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  • アズワン株式会社 試薬ビジネスグループ
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  • FAX:06-6447-8939
  • E-mail:Reagents@so.as-1.co.jp

仕様

  • 製品名:Smad4 Polyclonal Antibody
  • 略名:Smad4
  • 研究領域:Cancer
  • 製品説明:This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.SMAD4 (SMAD Family Member 4) is a Protein Coding gene. Diseases associated with SMAD4 include Myhre Syndrome and Polyposis, Juvenile Intestinal. Among its related pathways are PEDF Induced Signaling and Validated targets of C-MYC transcriptional repression. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is SMAD9.
  • 抗原:Synthesized peptide derived from the N-terminal region of human Smad4
  • 免疫動物:Rabbit
  • アイソタイプ:IgG
  • 種交差性:Human,Mouse,Rat,Monkey
  • Clone №:
  • Gene ID:4089
  • Gene Accession:
  • Protein Accession No:Q13485
  • アプリケーション:IHC-p,IF,ELISA
  • 標識:Unconjugated
  • 抗体種別:Polyclonal
  • バッファー:PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • 濃度:1mg/mL
  • 容量:60μL
  • 研究専用試薬です。本製品の使用は、研究用に限定して販売しております。医薬品の製造、診断、臨床検査用途には使用できません。

※この商品は別途費用が発生する場合があります。

アズワン品番 89-6315-19
型番 E-AB-34159
JANコード 0000000000000
標準価格 36,000円(税抜)
WEB価格
定額送料[?] 1,000円(税抜)
入り数 1個
アズワン在庫 [?]
サプライヤ在庫 [?]
出荷予定日
数量