86-7934-25 ［取扱停止］Human Fc gamma RI / CD64 Protein, His Tag (SPR & BLI & MALS verified) 50ug FCA-H52H1
特徴
- Background：Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16.
- Fc gamma RI binds IgG with high affinity and functions during early immune responses.
- Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses.
- High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family.
- FCGR1A / CD64 contains 3 Ig-like C2-type (immunoglobulin-like) domains.
- CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.
仕様
- サイズ：50ug
- Source：Human CD64, His Tag (FCA-H52H1) is expressed from human 293 cells (HEK293). It contains AA Gln 16 - Leu 281 (Accession # P12314-1).
- Molecule：Fc gamma RI / CD64
- Synonyms：FCGR1A,FCG1,FCGR1,IGFR1,CD64,CD64A,FCRI
- Species：Human
- Tag：His Tag
- Expression Systems：HEK293
- Expression Rigeion：Gln 16 - Leu 281
- Conjugate：Unconjugated
- Accession：NP_000557.1
- Molecular Weight：31.8 kDa
- Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 31.8 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：50ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7934-25
Human Fc gamma RI / CD64 Protein, His Tag (SPR & BLI & MALS verified) 50ug
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86-7934-26
Human Fc gamma RI / CD64 Protein, His Tag (SPR & BLI & MALS verified) 100ug
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