86-7934-10 ［取扱停止］Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified) 100ug FC4-M52H3
特徴
- Background：FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma .
- Also acts as a receptor for the Fc region of immunoglobulin epsilon .
- Binds with intermediate affinity to both IgG2a and IgG2b .
- Does not display binding to IgG1 or IgG3.
- Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a.
- Binds with low affinity to both the a and b allotypes of IgE.
- Has also been shown to bind to IgE allotype a only but not to allotype b.
- Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions
仕様
- サイズ：100ug
- Source：Mouse CD16-2, His Tag (FC4-M52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Gln 203 (Accession # A0A0B4J1G0-1).
- Molecule：Fc gamma RIV / CD16-2
- Synonyms：Fc gamma RIV,CD16-2,Fcgr4
- Species：Mouse
- Tag：His Tag
- Expression Systems：HEK293
- Expression Rigeion：Gly 21 - Gln 203
- Conjugate：Unconjugated
- Accession：NP_653142.2
- Molecular Weight：22.8 kDa
- Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.8 kDa. The protein migrates as 28-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：100ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7934-10
Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified) 100ug
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86-7934-09
Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified) 50ug
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