Background：MIS RII (Mullerian inhibiting substance type II receptor), also known as AMHRII (anti-Mullerian hormone type II receptor), is a serine/threonine receptor with a single transmembrane domain that belongs to the family of type II receptors of the TGF-beta superfamily.
Mutations in MIS RII result in persistent Mullerian duct syndrome (PMDS), persistent Müllerian duct syndrome (PMDS) is a sex-limited disorder in which males develop portions of the female reproductive tract.
Anti-Müllerian hormone (AMH) and its receptor (AMHR2) induce the regression of the Müllerian ducts in male embryos, but the mechanism by which the Amhr2 gene is specifically activated is not fully understood.
仕様
サイズ：100ug
Source：Cynomolgus MIS RII, His Tag (MII-C52H5) is expressed from human 293 cells (HEK293). It contains AA Pro 18 - Ser 144 (Accession # A0A2K5U1R9-1).
Molecule：MIS RII
Synonyms：MIS RII,MRII,AMHR2,AMHR,MISR2,AMH type II receptor
Species：Cynomolgus
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Pro 18 - Ser 144
Conjugate：Unconjugated
Molecular Weight：15.4 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.4 kDa. The protein migrates as 20-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
