Background:Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family.
IFNAR1 /IFNAR contains four fibronectin type-III domains.
IFNAR1 associates with IFNAR2 to form the type I interferon receptor.
IFNAR1 is receptor for interferons alpha and beta.
IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
仕様
サイズ:100ug
Source:Mouse IFN-alpha / beta R1, His Tag (IF1-M5225) is expressed from human 293 cells (HEK293). It contains AA Glu 27 - Thr 429 (Accession # P33896-1).
Molecule:IFN-alpha/beta R1
Synonyms:IFNAR1,IFNAR,CRF2-1,IFN-R-1,IFNAR-1
Species:Mouse
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Glu 27 - Thr 429
Conjugate:Unconjugated
Accession:NP_034638.2
Molecular Weight:47.6 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.6 kDa. The protein migrates as 57-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.