Background：GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG.
Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration.
GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
仕様
サイズ：100ug
Source：Human GAS6, His Tag (GA6-H5249) is expressed from human 293 cells (HEK293). It contains AA Asp 279 - Ala 678 (Accession # Q14393-2).
Molecule：GAS6
Synonyms：GAS6,GAS-6,AXLLG
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Asp 279 - Ala 678
Conjugate：Unconjugated
Accession：NP_000811.1
Molecular Weight：46.0 kDa
Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 46.0 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
