Background：Amyloid precursor protein (APP) is a type 1 membrane protein with an NH2 -terminal extracellular domain and a COOH-terminal cytosolic tail.
The amyloid precursor protein (APP) takes a key role in Alzheimer’s disease (AD) pathogenesis.
Processing of APP generates that generates the Aβ peptide, whose accumulation is associated with Alzheimer’s disease.
仕様
サイズ：100ug
Source：Human Amyloid Precursor, His Tag (AMR-H52H4) is expressed from human 293 cells (HEK293). It contains AA Leu 18 - Ala 701 (Accession # P05067-1).
Molecule：Amyloid Precursor Protein
Synonyms：Amyloid Precursor Protein,Alzheimer disease amyloid protein,APP,Amyloid-beta precursor protein
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Leu 18 - Ala 701
Conjugate：Unconjugated
Accession：NP_000475.1
Molecular Weight：79.3 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 79.3 kDa. The protein migrates as 80-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
