86-7932-52 ［取扱停止］Mouse IgG2b Fc Protein, Tag Free (MALS verified) 1mg IGB-M5203
特徴
- Background：Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells.
- In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment.
- The Fc segment bears a highly conserved N-glycosylation site.
- There are two members of IgG2: IgG2a and IgG2b.
- It was found that IgG2a was superior to IgG1 in activating complement.
- The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.
- Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).
仕様
- サイズ：1mg
- Source：Mouse IgG2b Fc, Tag Free (IGB-M5203) is expressed from human 293 cells (HEK293). It contains AA Glu 97 - Lys 335 (Accession # P01867-2).
- Molecule：IgG2b Fc
- Synonyms：IgG2B,IgG2b Fc
- Species：Mouse
- Tag：Tag Free
- Expression Systems：HEK293
- Expression Rigeion：Glu 97 - Lys 335
- Conjugate：Unconjugated
- Molecular Weight：26.7 kDa
- Characteristics：This protein carries no "tag". The protein has a calculated MW of 26.7 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Package Size：1mg*1
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7932-51
Mouse IgG2b Fc Protein, Tag Free (MALS verified) 200ug
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86-7932-52
Mouse IgG2b Fc Protein, Tag Free (MALS verified) 1mg
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