Background：Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells.
In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment.
The Fc segment bears a highly conserved N-glycosylation site.
There are two members of IgG2: IgG2a and IgG2b.
It was found that IgG2a was superior to IgG1 in activating complement.
The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.
仕様
サイズ：25ug
Source：Biotinylated Mouse IgG2a Fc, Avitag (IGA-M8216) is expressed from human 293 cells (HEK293). It contains AA Glu 98 - Lys 330 (Accession # P01863-1).
Molecule：IgG2a Fc
Synonyms：IgG2A
Species：Mouse
Tag：Avi Tag
Expression Systems：HEK293
Expression Rigeion：Glu 98 - Lys 330
Conjugate：Precision Avi
Molecular Weight：38.0 kDa
Characteristics：This protein carries an Avi tag at the C-terminus. The protein has a calculated MW of 38.0 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
