86-7932-45 ［取扱停止］Llama IgG2b Fc Protein, Tag Free (MALS verified) 1mg IGB-L5204
特徴
- Background：Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells.
- In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment.
- The Fc segment bears a highly conserved N-glycosylation site.
- There are two members of IgG2: IgG2a and IgG2b.
- It was found that IgG2a was superior to IgG1 in activating complement.
- The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.
- Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).
仕様
- サイズ：1mg
- Source：Llama IgG2b Fc, Tag Free (IGB-L5204) is expressed from human 293 cells (HEK293). It contains AA Glu 1-Ser 243 (Accession # AAX73259.1).
- Molecule：IgG2b Fc
- Synonyms：IgG2B,IgG2b Fc
- Species：Llama
- Tag：Tag Free
- Expression Systems：HEK293
- Expression Rigeion：Glu 1-Ser 243
- Conjugate：Unconjugated
- Accession：AAX73259.1
- Molecular Weight：27.3 kDa
- Characteristics：This protein carries no "tag". The protein has a calculated MW of 27.3 kDa. The protein migrates as 35-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
- Package Size：500ug*2
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7932-45
Llama IgG2b Fc Protein, Tag Free (MALS verified) 1mg
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86-7932-44
Llama IgG2b Fc Protein, Tag Free (MALS verified) 200ug
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