86-7932-35 ［取扱停止］Human IgG2 Fc Protein, Tag Free (MALS & SPR verified) 200ug IG2-H5206
特徴
- Background：Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells.
- In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment.
- The Fc segment bears a highly conserved N-glycosylation site.
- There are two members of IgG2: IgG2a and IgG2b.
- It was found that IgG2a was superior to IgG1 in activating complement.
- The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.
- Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).
仕様
- サイズ：200ug
- Source：Human IgG2 Fc, Tag Free (IG2-H5206) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 326 (Accession # P01859-1).
- Molecule：IgG2 Fc
- Synonyms：IGHG2
- Species：Human
- Tag：Tag Free
- Expression Systems：HEK293
- Expression Rigeion：Glu 99 - Lys 326
- Conjugate：Unconjugated
- Molecular Weight：25.7 kDa
- Characteristics：This protein carries no "tag". The protein has a calculated MW of 25.7 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：200ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7932-35
Human IgG2 Fc Protein, Tag Free (MALS & SPR verified) 200ug
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86-7932-34
Human IgG2 Fc Protein, Tag Free (MALS & SPR verified) 1mg
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掲載カタログ情報
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