Background：Nucleolin is the major nucleolar protein of growing eukaryotic cells.
It is found associated with intranucleolar chromatin and pre-ribosomal particles.
It induces chromatin decondensation by binding to histone H1.
It is thought to play a role in pre-rRNA transcription and ribosome assembly.
May play a role in the process of transcriptional elongation.
Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
仕様
サイズ：100ug
Source：Human Nucleolin, Mouse IgG2a Fc Tag (NUL-H5254) is expressed from human 293 cells (HEK293). It contains AA Val 2 - Glu 710 (Accession # P19338-1).
Molecule：Nucleolin
Synonyms：Nucleolin,NCL,Protein C23
Species：Human
Tag：Mouse IgG Fc Tag
Expression Systems：HEK293
Expression Rigeion：Val 2 - Glu 710
Conjugate：Unconjugated
Accession：NP_005372.2
Molecular Weight：103.5 kDa
Characteristics：This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 103.5 kDa. The protein migrates as 130-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 0.1 EU per ug by the LAL method.
