Background：Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers.
GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail.
The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains.
GPA33 may play a role in cell-cell recognition and signaling.
仕様
サイズ：50ug
Source：Human GPA33, Fc Tag (GP3-H5253) is expressed from human 293 cells (HEK293). It contains AA Ile 22 - Val 235 (Accession # Q99795-1).
Molecule：GPA33
Synonyms：GPA33,A33
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Ile 22 - Val 235
Conjugate：Unconjugated
Accession：NP_005805.1
Molecular Weight：50.1 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.1 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
