Background：Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9.
4-1BBL is the high affinity ligand of 4-1BB.
4-1BBL induces the proliferation of activated peripheral blood T-cells.
Also, 4-1BBL may have a role in activation-induced cell death (AICD).
Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages.
As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
仕様
サイズ：100ug
Source：Rat 4-1BB Ligand His,Flag Tag (41L-R52D3) is expressed from human 293 cells (HEK293). It contains AA Pro 106 - Gly 308 (Accession # Q80WE6-1).
Molecule：4-1BB Ligand
Synonyms：4-1BB Ligand,TNFSF9,CD137L
Species：Rat
Tag：His Tag & Flag Tag
Expression Systems：HEK293
Expression Rigeion：Pro 106 - Gly 308
Conjugate：Unconjugated
Accession：NP_852049.1
Molecular Weight：72.3 kDa
Characteristics：This protein carries a polyhistidine tag at the N-terminus, followed by a flag tag. The protein has a calculated MW of 72.3 kDa. The protein migrates as 95-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
