discovered as complexes with mannose-binding lectin (MBL) and therefore named MBL-associated
serine proteases, but later, they were found to interact with ficolins, and later still, collectin-10
and collectin-11.
As well as proteolytic enzymes (MASP-1, MASP-2, MASP-3), the group includes
non-enzymatic factors (MAp19, MAp44).
In this review, the association-specific factors of the lectin
pathway with haematologic malignancies and related infections are discussed.
仕様
サイズ:20ug
Source:Human MASP3, His Tag (MA3-H5243) is expressed from human 293 cells (HEK293). It contains AA Gly 298 - Val 721 (Accession # P48740-2).
Molecule:MASP3
Synonyms:MASP3, MASP1, CRARF1, RaRF
Species:Human
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Gly 298 - Val 721
Conjugate:Unconjugated
Accession:NP_624302.1
Molecular Weight:48.7 kDa
Characteristics:This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 48.7 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.